Management of SDS is critical for companies involved in handling harmful substances to stay compliant with regulatory requirements and employee safety. The best SDS management software products ensure that SDS organization, chemical surveillance, and requirements for reporting become simpler, thereby enabling manufacturing, healthcare, lab, and environmental agencies to be able to uphold safety measures. The software also assists safety managers, compliance managers, and EHS professionals in their tasks using automation, tracking in real-time, and assessing risks.
The selection criteria of the following discussed best SDS management tools are regulatory compliance capability, ease of use, automation, scalability, and integration. Through SDS management software, organizations can enhance safety processes, reduce compliance risk, and improve efficiency in managing chemical data, ensuring safer and more compliant workplaces amidst evolving regulations.
What does an SDS Management Software do?
An SDS or Safety Data Sheet is a sheet providing information regarding the chemical substances’ properties, hazards, safe handling, and emergency procedures. It is one of the major tools in workplace safety that sensitizes workers and organizations to the dangers associated with hazardous materials and compliance with regulatory requirements under OSHA’s Hazard Communication Standard (HCS) and Globally Harmonized System (GHS).
Software for Management of SDS (Safety Data Sheet) helps enterprises keep their SDS documents well organized, maintain records, and ready for reference. It enforces compliance automatically, has chemicals tracked for inventories, and sends out prompt alerts about new developments in regulatory compliance. Providing easy cloud access, extensive searching facilities, and synchronization with EHS systems, it automates hazard communication and prevents probable compliance violations. The software proves valuable to enterprises using chemicals across sectors such as manufacturing, health, drugs, and building industries.
Criteria for Selecting the Best SDS Management Software
Selecting the best SDS management software takes the most important parameters into account that offer efficiency, compliance, and usability. Listed here are the most important parameters:
- Regulatory Compliance Requirements: Software should include room for OSHA, GHS, WHMIS, REACH, and other industry standards as a way in which companies can stay compliant with safety regulations.
- SDS Automatic Updates: Software should update SDS documents automatically with the latest regulatory changes and safety information of chemicals.
- Inventory Management of Chemicals: Software should allow organizations to manage, classify, and handle hazardous materials efficiently.
- Easy-to-Use Interface: An easy-to-use and intuitive dashboard facilitates ease of use by employees and safety managers.
- Integration Features: Integration of ERP software and EHS system promotes workflow.
- Accessibility & Cloud Support: Cloud-based systems allow remote access to SDS documents from any location and on any device.
- Customization & Reporting: Robust reporting features and customizable features allow organizations to customize SDS management based on their needs.
- Multi-Language Support: For global operation needs, SDS software should be able to support various languages for region compliance.
- Security & Data Protection: SDS hazardous documents should be encrypted and protected with access control.
- Scalability & Pricing: The software should be scalable to accommodate small businesses and large businesses with varied pricing.
These factors allow organizations to select aninces management system that enhances safety, enhances compliance, and maximizes chemical data management.
Comparison Between Best SDS Management Software
Here’s a detailed comparison table for the best SDS management software, including features, pricing, use cases, and official websites.
Software | Key Features | Pricing | Use Cases | Website |
Chemwatch | SDS authoring, chemical inventory tracking, regulatory compliance, risk assessment, automated updates | Custom pricing | Best for enterprises needing global regulatory compliance | chemwatch.net |
SiteHawk | Cloud-based SDS management, chemical data analysis, reporting tools, compliance tracking | Custom pricing | Ideal for manufacturers and industrial facilities | ul.com/sitehawk |
MSDSonline (VelocityEHS) | SDS and chemical inventory management, compliance reporting, mobile access | Custom pricing | Suitable for businesses seeking mobile SDS access | ehs.com |
SpheraCloud | SDS database, regulatory updates, chemical hazard assessments, supply chain compliance | Custom pricing | Best for large corporations managing complex compliance | sphera.com |
EcoOnline | SDS and chemical safety management, environmental compliance, risk assessments | Custom pricing | Designed for businesses focused on sustainability | ecoonline.com |
Safetec | SDS tracking, compliance automation, real-time updates, document storage | Custom pricing | Ideal for laboratories and healthcare organizations | safetec.com |
ERA SDS Management | SDS organization, regulatory compliance automation, document control, chemical safety training | Custom pricing | Best for businesses prioritizing employee safety | era-environmental.com |
KHA Online-SDS | Centralized SDS database, compliance tracking, chemical classification, automated SDS updates | Custom pricing | Suitable for healthcare, education, and manufacturing | kha.com |
3E Protect (Verisk 3E) | SDS updates, chemical inventory management, regulatory tracking, multilingual support, 24/7 SDS access | Custom pricing | Ideal for multinational companies | verisk3e.com |
Quantum SDS | Cloud-based SDS access, compliance tracking, regulatory alerts, risk assessment tools | Custom pricing | Best for small to mid-sized businesses | sdsquantum.com |
SDSpro | Centralized SDS repository, barcode scanning, multi-regulatory compliance (OSHA, GHS, WHMIS), automated updates | Custom pricing | Suitable for healthcare, industrial, and manufacturing | sds-pro.com |
Dakota SDS Management | Real-time SDS access, chemical inventory tracking, workplace safety integration | Custom pricing | Best for large organizations managing hazardous materials | dakotasoft.com |
Toxnot | SDS management, sustainability tracking, supply chain transparency, chemical ingredient analysis | Custom pricing | Ideal for companies prioritizing eco-friendly compliance | toxnot.com |
Enablon SDS Management | SDS storage, regulatory reporting, chemical safety analysis, compliance monitoring | Custom pricing | Best for enterprise-level businesses | enablon.com |
List of 15 Best SDS Management Software
1. Chemwatch

Chemwatch is a robust SDS management software that facilitates effective chemical safety data sheets in organizations. Chemwatch offers auto-updated SDS, regulatory compliance monitoring, and chemical risk profiling. The program offers multilingual authoring of SDS and real-time hazard identification. Chemwatch offers inventory tracking and chemical label functionality. It supports a huge worldwide SDS database with an extensive regulatory database for aligning enterprises globally as per laws like OSHA, REACH, and GHS. It is suitable for companies that deal with massive amounts of hazardous chemicals.
Key Features:
- Comprehensive SDS database with real-time updates
- Automated chemical risk assessment and hazard classification
- Integration with regulatory databases for compliance tracking
- Multi-language support for global accessibility
Pros:
- Extensive regulatory compliance coverage
- User-friendly interface with powerful search capabilities
Cons:
- Higher pricing compared to some competitors
- May have a learning curve for new users
Pricing:
Contact for a quote
Who Should Use It?
Ideal for large enterprises and industries with complex chemical safety needs, such as manufacturing, pharmaceuticals, and oil & gas.
2. SiteHawk

SiteHawk is a cloud solution SDS management system that helps organizations automate tracking chemical information and regulation compliance. SiteHawk offers users a way to keep, organize, and view SDS documents at hand while maintaining compliance with regulations. SiteHawk has some components like control over chemical inventory, regulatory reporting, and workplace labeling. It also accommodates other integrations for EHS systems. The system’s ease of use and real-time risk calculation ability make it an ideal solution for use in manufacturing, healthcare, and industry.
Key Features:
- Centralized SDS and chemical inventory management
- Real-time regulatory updates and compliance tracking
- Barcode scanning for quick inventory tracking
- Customizable safety labels and reports
Pros:
- Easy integration with existing EHS systems
- Mobile-friendly interface for on-the-go access
Cons:
- Advanced features may require additional training
- Limited offline access
Pricing:
Contact for pricing details
Who Should Use It?
Best suited for mid-to-large organizations in construction, manufacturing, and healthcare that need efficient chemical inventory tracking.
3. MSDSonline

MSDSonline, which is now owned by VelocityEHS, is a top SDS management platform that ensures organizations remain OSHA- and other world safety-standard compliant. It features centralized storage of SDS documents, computerized updates, and access to a comprehensive SDS library. The system includes chemical inventory management, workplace labeling, and safety training applications. It is also mobile-compatible so that employees can access the SDS documents on the move. MSDSonline is being extensively used across pharmaceutical, construction, and education sectors due to its simplicity and consistency.
Key Features:
- Extensive SDS database with automated updates
- Chemical inventory management with reporting tools
- OSHA and GHS compliance tracking
- Mobile access for field workers
Pros:
- Intuitive user interface with easy navigation
- Strong compliance support for regulatory requirements
Cons:
- Can be expensive for small businesses
- Limited customization options for reports
Pricing:
Subscription-based; contact for details
Who Should Use It?
Ideal for companies in manufacturing, healthcare, and education needing OSHA compliance and centralized SDS access.
4. SpheraCloud

SpheraCloud is a next-generation SDS and chemical management software that is best suited for enterprise-wide compliance. It offers automated revision of SDS, regulatory tracking, and hazardous material management. It also includes EHS systems to enhance risk assessment and workplace safety. SpheraCloud provides real-time chemical inventory analysis and predictive analytics for risk mitigation. Its cloud-based design offers scalability as well as data security, which makes it the best solution for large-scale manufacturing, energy, and chemical industries.
Key Features:
- AI-powered SDS authoring and hazard classification
- Automated compliance tracking with global regulations
- Integrated risk assessment and safety reporting
- Cloud-based platform with real-time updates
Pros:
- Scalable solution for large enterprises
- Strong data analytics and reporting capabilities
Cons:
- Higher cost compared to smaller-scale solutions
- Requires training for full feature utilization
Pricing:
Custom pricing available upon request
Who Should Use It?
Best for global enterprises in industries such as oil & gas, pharmaceuticals, and chemicals that require high-level compliance management.
5. EcoOnline

EcoOnline offers a simple SDS management system to ensure workplace safety and compliance. The system enables firms to store, update, and simply monitor SDS documents. It offers features such as risk assessment, chemical approval workflows, and real-time safety reminders. EcoOnline features multi-location inventory management, so it is perfect for large companies with branches too. Its ease and compliance monitoring features make it the right choice for firms interested in simplifying chemical safety management.
Key Features:
- Cloud-based SDS storage and retrieval
- Chemical inventory tracking with barcode scanning
- Automatic compliance alerts for hazardous substances
- Multi-language support for global teams
Pros:
- Intuitive interface with easy-to-use tools
- Strong focus on environmental safety compliance
Cons:
- Limited customization for advanced users
- May not be ideal for highly complex chemical inventories
Pricing:
Contact for pricing details
Who Should Use It?
Ideal for SMEs and large organizations looking for a simple and effective EHS-focused SDS management solution.
6. Safetec

Safetec is an SDS management platform delivered from the cloud that makes chemical safety compliance easier. It provides instant access to SDS documents, chemical inventory monitoring, and regulatory compliance reporting. Safetec’s program automatically ensures SDS records are updated with the most recent safety information. The software is mobile-enabled, where employees can access SDS data in real time. Its strong security and compliance monitoring make it an ideal choice for companies working with hazardous materials.
Key Features:
- Centralized SDS repository with search capabilities
- Automated compliance tracking for OSHA and GHS
- Custom labeling and reporting tools
- Mobile access for quick data retrieval
Pros:
- User-friendly interface with minimal learning curve
- Strong customer support and training resources
Cons:
- Limited advanced analytics features
- May not be suitable for complex enterprise-level needs
Pricing:
Available upon request
Who Should Use It?
Best for small to mid-sized businesses looking for an affordable and easy-to-use SDS management solution.
7. ERA SDS Management

ERA SDS Management offers companies an end-to-end solution for managing safety data sheets and regulatory compliance. The software automates SDS updates, creates workplace labels, and provides chemical hazard classification tools. ERA integrates with a range of EHS systems to simplify risk management and compliance with OSHA, GHS, and REACH regulations. It is a great option for companies looking for a scalable and automation-based SDS management system.
Key Features:
- Cloud-based SDS storage with real-time updates
- Automated chemical hazard classification
- Compliance tracking for multiple regulations (OSHA, GHS, etc.)
- Integrated environmental impact analysis tools
Pros:
- Strong emphasis on sustainability and green compliance
- Scalable for both small businesses and large enterprises
Cons:
- Requires training for full utilization
- Higher pricing compared to basic SDS solutions
Pricing:
Custom pricing based on company size and needs
Who Should Use It?
Ideal for companies in manufacturing, automotive, and chemicals that need advanced environmental and regulatory tracking.
8. KHA Online-SDS

KHA Online-SDS is an evolving SDS management software that eases chemical data management and regulatory compliance. It has a centralized SDS database that provides instant access to chemical safety information. Compliance tracking, automated updates, and reporting of regulatory compliance as per requirements are provided by the software. Hazard classification is also supported by KHA Online-SDS, and it also supports integration with workplace safety software. Its mobility and simplicity make it perfect for usage in the fields of manufacturing, education, and healthcare, where precise SDS retrieval is crucial to safety.
Key Features:
- Secure cloud-based SDS repository
- Real-time regulatory updates and alerts
- Advanced search and filter options
- Integration with safety training programs
Pros:
- Affordable pricing for small businesses
- Easy-to-use interface with comprehensive search features
Cons:
- Limited automation compared to enterprise-grade solutions
- Basic reporting capabilities
Pricing:
Available upon request
Who Should Use It?
Great for small and mid-sized businesses looking for a cost-effective SDS management solution with essential compliance features.
9. Enablon SDS Management

Enablon SDS Management is an enterprise-grade software designed to make business easier with respect to safety data sheet management and chemical compliance. It features automatic SDS updates, regulatory reporting, and live tracking of chemicals. Enablon connects with general EHS management systems to bring about an all-around solution to workplace safety and regulatory compliance. Its superior analytics and compliance monitoring features are sought after by big companies who want a scalable and all-inclusive SDS management system
Key Features:
- Automated SDS tracking and regulatory compliance updates
- Advanced chemical hazard assessment tools
- Integration with EHS and risk management systems
- Customizable workflows for safety reporting
Pros:
- Highly scalable for global enterprises
- Strong automation features for compliance tracking
Cons:
- Complex setup process requiring dedicated IT support
- Premium pricing structure
Pricing:
Available upon request
Who Should Use It?
Best for large corporations and industries that require a sophisticated, enterprise-level SDS management solution.
10. 3E Protect

3E Protect by Verisk 3E is a top SDS management solution that gives real-time access to safety data sheets and regulatory data. It includes automated updates of SDS, tracking of chemicals, and reporting on compliance. The software easily integrates with EHS management systems to facilitate hazard communication and workplace safety. With multilingual functionality and 24/7 availability, 3E Protect is a go-to option for multinational companies that need a strong and reliable SDS management platform for regulatory compliance.
Key Features:
- 24/7 cloud-based access to an extensive SDS database
- Real-time regulatory updates and compliance tracking
- Chemical inventory management with automated hazard assessments
- Integration with EHS platforms and ERP systems
Pros:
- Comprehensive regulatory coverage for global compliance
- Strong customer support and training resources
Cons:
- Higher pricing compared to some alternatives
- Requires training to maximize all features
Pricing:
Custom pricing based on company size and requirements
Who Should Use It?
Ideal for enterprises and organizations handling complex chemical inventories that require strict regulatory compliance.
11. Quantum SDS

Quantum SDS is a contemporary cloud-based SDS management system developed to track chemical safety data effectively and comply with regulations. It provides automatic updates of SDS, regulatory real-time alerts, and detailed chemical inventory management. It features workplace labeling software and risk assessment platform integration to supplement safety initiatives. It features ease of use and scalability, which has made it a leader among small to mid-sized organizations that need an efficient way to manage chemical safety documents.
Key Features:
- Centralized SDS storage with advanced search functions
- Chemical hazard classification and risk assessment tools
- Custom reporting and labeling features
- Automated regulatory compliance tracking
Pros:
- Strong customization options for safety documentation
- User-friendly interface with efficient search functionality
Cons:
- Lacks deep integration with third-party software
- Limited scalability for very large enterprises
Pricing:
Available upon request
Who Should Use It?
Best suited for mid-sized businesses needing a cost-effective SDS management tool with strong customization capabilities.
12. SDSpro

SDSpro is an extremely efficient SDS management software that assists companies in ensuring chemical safety compliance with ease. It consolidates SDS storage, auto-updates, and offers real-time compliance tracking. SDSpro also includes barcode scanning for chemical identification and accommodates OSHA, GHS, and WHMIS regulation systems. The strong reporting features and adjustable customizations of the platform make it efficient for a wide range of industries, such as healthcare, manufacturing, and research, where precise SDS documentation and compliance are essential.
Key Features:
- Cloud and on-premise SDS storage options
- Automated chemical inventory tracking
- Mobile access for quick retrieval of safety data
- OSHA, WHMIS, and GHS compliance support
Pros:
- Offers both cloud-based and offline solutions
- Intuitive and user-friendly design
Cons:
- Limited automation compared to larger enterprise solutions
- Reporting features could be more advanced
Pricing:
Contact for a quote
Who Should Use It?
Ideal for small to mid-sized businesses looking for a flexible SDS management system with on-premise options.
13. Dakota SDS Management

Dakota SDS Management is an influential cloud-based tool for compliance and organization of safety data sheets. It gives immediate SDS access, an automatic update feature, and inventory chemical tracking. It can be incorporated into workplace safety programs to improve hazard communication and reporting regulatory compliance. Dakota SDS Management is valuable for industries that work with huge amounts of hazardous chemicals and need to attain a more organized system for efficient management of safety documents.
Key Features:
- Cloud-based SDS access with real-time updates
- Chemical inventory tracking with reporting tools
- Compliance management for OSHA and GHS standards
- Custom safety training and documentation features
Pros:
- Strong compliance tracking and regulatory updates
- Scalable for large enterprises with complex safety needs
Cons:
- Pricing may be high for smaller businesses
- Requires setup and training for optimal use
Pricing:
Custom pricing available upon request
Who Should Use It?
Best for large enterprises and industries requiring high-level safety and compliance tracking, such as pharmaceuticals and chemicals.
14. Toxnot

Toxnot is an innovative SDS and chemical regulatory compliance software designed with sustainability and transparency in mind. It helps companies track chemical ingredients, manage SDS documents, and ensure regulatory compliance. In addition, Toxnot has product lifecycle tests, supplier data management capabilities, and reporting to ensure improved chemical safety. Toxnot is an excellent solution for organizations wishing to integrate sustainability into their chemical management practices in compliance with international safety standards.
Key Features:
- Cloud-based SDS storage with global compliance support
- Automated chemical hazard assessments and reporting
- Supplier engagement tools for chemical data collection
- Sustainability tracking for environmental impact analysis
Pros:
- Excellent for companies focusing on sustainability and green initiatives
- Strong collaboration tools for supply chain compliance
Cons:
- May not be suitable for small businesses with simple SDS needs
- Higher pricing compared to basic SDS tools
Pricing:
Contact for pricing details
Who Should Use It?
Ideal for enterprises in manufacturing, retail, and chemicals that prioritize sustainability and supply chain transparency.
Conclusion
The choice of best SDS management software ultimately depends on the specific needs of an organization. Chemwatch and MSDSonline (VelocityEHS) are best for big companies that require high-level compliance features and global regulatory support. SiteHawk and SpheraCloud offer powerful reporting capabilities and EHS system integration, so they are well-suited to organizations with highly sophisticated safety requirements. Small and medium-sized businesses utilize low-cost but effective options like SDSpro, Hazox, and Quantum SDS, providing required compliance monitoring without undue complexity.
For companies with a focus on sustainability and transparency, Toxnot stands out in particular with its product lifecycle analysis. Companies seeking end-to-end risk management and automation might consider Enablon SDS Management. From regulatory compliance through improved chemicals’ inventory management to immediate access to SDSs, these products ensure greater workplace safety and process effectiveness across several market segments.
FAQs
1. What is SDS management software?
SDS management software is a computer-based program that aids businesses in the storage, organization, and retrieval of Safety Data Sheets (SDS) with ease. It places businesses in conformity with regulations such as OSHA, GHS, and WHMIS through real-time alerts, hazard categorization, and chemical tracking.
2. Who needs SDS management software?
Industries dealing with hazardous chemicals, such as manufacturing, healthcare, construction, and chemical processing, need SDS management software for workplace safety and regulatory compliance.
3. What do I want to look for in the best SDS management software?
The key features in the best SDS management software include cloud storage of SDSs, automatic updates, compliance tracking, chemical inventory tracking, reporting capabilities, and mobile access for retrieval of real-time data.
4. Is SDS management software expensive?
It varies with the features and size of the company. Some systems offer free versions or tiered pricing models, so they might be affordable for small companies as well as large companies.
5. What is the best SDS management software for small businesses?
SDSpro, Hazox, and Quantum SDS are cost-effective offerings with basic interfaces that make them great options for small to mid-size companies needing basic SDS management functionality.